'Pyar Ko Ho Jaane Do‘ follows the life journey of Ishan and Preet. They are part of the Hooda family, an extremely prosperous business family of Delhi. The family has many businesses across industries but the crown jewel of their business is their arms business with the Indian government. Mr Hooda and Mrs. Hooda have three children - Trisha, Niti and Sid. Ishan (Iqbal Khan) is the nephew of Mr. Hooda and is married to Preet (Mona Singh). Ishan and Preet are the perfect couple and never seem to tire of their efforts to keep the entire family together.

Kavya and Ani are a married couple. They live together, but are estranged from one another. They are both having long-standing extramarital affairs—she with Vikram and he with Nora.

Khushi and Arnav have diametrically opposite ideologies. If Khushi believes in means, Arnav believes only in ends. Khushi's relationships are the most important to her, whereas Arnav believes all people come with a price and can be manipulated for one's benefit.

Mohit, a young man raised into beliving in fairy tales, comes to Bombay to find Manisha, a young woman whom he saved from drowning in a lake near his village, whom he belives to be an actual mermaid princess.

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When a single mother her teenage daughter becomes ensnared in a deadly crime, find an unexpected ally in their neighbor, a simple, doting but genius teacher math teacher comes to aid, while a tenacious cop digs into the case.

Anupam embarks on an ambitious project to create a Bollywood music video for Aa Jaane Jaa. He casts the dashing Hrithik and the stunning Deepika as the lead models, with support from his other friends, including Ranjeet. During the shoot, Hrithik and Deepika's on-screen chemistry transforms into real love. However, their happiness is threatened by Amjad, who envies their bond and seeks to disrupt their lives. One day, the tension escalates in a jungle setting where Hrithik and Amjad face off in a fierce fight. With the unexpected help of Ranjeet, Hrithik emerges victorious, protecting his love and ensuring their bond remains unshaken. The music video ends with Hrithik and Deepika growing closer, reaffirming the message that true love never dies, no matter the challenges.

Ashwin is a photographer, covering the upcoming elections for a newspaper. His life gets entangled with politics when one of his published photographs upsets a corrupt political party.